Sunday, September 27, 2009

GH and DHEA - Should you seriously consider taking them? A look at the evidence...

In the medical field Hormone Replacement Therapy, especially in women, has not worked out the way they were originally hoping it would. In many cases it increased cancer rates and increased the risk of stroke and heart attacks, especially the hormones that are synthesized from animals, like Premarin.

In the nutritional world, 2 hormones derived from natural sources have had major benefits in some and mixed benefits in others. These 2 hormones are DHEA, a master adrenal hormone and GH, Growth Hormone, produced normally by the pituitary gland.

These 2 hormones produce all the other hormones we need, but tend to decline as we age. I have listed articles below for you to evaluate and consider. They are reliable sources and will give you the information you need to decide if they might be worth trying in your case.

Life extensionists use and recommend these products as a way to reverse age related issues associated with declining hormone levels found in aging adults.
I have also listed at the bottom a great source for product, if you decide you are interested. MBI, or Molecular Biologics has been around for over 25 years, and the products are formulated by biochemist Ned Jensen. I have worked with Ned and his company since my early days in the San Francisco Bay Area. Ned explains the value of taking these products, so be sure to click on the links and read his comments, too.
Enjoy this week's articles, and remember...
You are never too old to get younger.

cw

DHEA Restoration Therapy - Hormone Replacement Therapy...
It's no accident that youth is associated with high levels of hormones. Produced throughout the body, sex hormones are critical to maintaining vibrancy and good health. In recent decades, scientists have begun to understand the powerful benefits of replacing hormones lost to aging. However, there are serious questions about the safety of conventional hormone replacement therapy, which relies on hormones that are synthesized from animals (Premarin ®) or created in a lab (Provera ®). Most recently, the widespread prescribing of these two hormones among menopausal women has come under scientific scrutiny because of the increased risk of stroke and heart attack.
As an alternative, bioidentical hormone replacement therapy may be one of the best things aging people can do for themselves because of the wide-ranging benefits of bioidentical hormones on everything from the cardiovascular system to the aging brain and bones. What is required, however, is an approach that harnesses the wisdom of the body and relies on bioidentical hormones to replace those that decline with age.
In 1981, Life Extension introduced dehydroepiandrosterone (DHEA) in an article that described the multiple anti-aging effects of this steroid hormone. At the time, DHEA replacement therapy was almost unheard of. Today, however, DHEA replacement therapy has been studied extensively, and decreased DHEA levels have been implicated in heart disease, high cholesterol, depression, inflammation, immune disorders, schizophrenia, Alzheimer's disease, diabetes, HIV, and osteoporosis (Hauffa BP et al 1984; Valenti G 2002; Valenti G et al 2004).



Why DHEA May Be the Best-Validated Anti-Aging Supplement...
Recently, new side effects were announced for the popular osteoporosis drug known as Fosamax®. Apparently, many Fosamax® users find themselves with the troubling condition known as osteonecrosis of the jaw, in which the jaw bone essentially dies. Unfortunately, those experiencing osteoporosis are presented with little choice other than to take the drug and hope for the best. Now, strong evidence suggests that ensuring optimal levels of DHEA may help to slow bone loss and guard against the crippling effects of osteoporosis.
Studies of both men and women have demonstrated that low levels of DHEA are associated with bone loss through mechanisms related to altered mineral absorption and metabolism, as well as through inflammatory processes. In younger people, normal DHEA levels stimulate adequate production of a substance called insulin-like growth factor 1, which maintains new bone formation. Healthy DHEA levels also suppress production of interleukin-6, an inflammatory cytokine that causes bone breakdown (resorption), thus preventing bone loss. Decreasing DHEA levels are associated with diminished levels of insulin-like growth factor 1 and higher levels of interleukin-6, creating a situation in which bone loss exceeds new bone formation.


DHEA: A Master Hormone in Search of Its Identity...
At sixty-seven, Amy Woolfe found that even getting out of bed in the morning took almost as much energy as she had. "I've gotten used to feeling bad," she told me. "It becomes a way of life." Amy, a mild diabetic, was so tired that I considered diagnosing her condition as Chronic Fatigue Syndrome. But, when I tried her out on DHEA, in less than thirty days she came back and told me, "I've never had so much energy in my life. I feel like I'm twenty-five again." That was three or four years ago, pretty early in my career as a doctor who prescribes hormones. I was amazed then; nowadays I hear similar stories from other men and women and am not surprised.


HUMAN GROWTH HORMONE TO CORRECT AGE-RELATED, ADULT GROWTH HORMONE DEFICIENCY...
Growth hormone, secreted by the pituitary gland, is a small protein-like hormone (peptide), similar to insulin. The HGH molecule is twice as large, however, making manufacture and administration more expensive. Commonly referred to as human growth hormone or "HGH," it is difficult to measure directly. HGH is secreted in very brief pulses during the early hours of sleep and remains in the circulation for only a few minutes. It is quickly bound to HGH receptors throughout the body, and some is taken into the liver and converted into somatomedin-C, another small peptide hormone (also known as insulin-like growth factor-one or IGF-I). IGF-1 is responsible for some but not all of the activity of growth hormone in the body. IGF-1 levels in the blood remain much more constant and can be measured in the laboratory as the most accurate indirect indicator of total daily HGH production. During adolescence, when growth is most rapid, production of HGH is very high. That is why it was named "growth hormone." Even after growth stops, however, growth hormone must continue to be present (at somewhat lower levels) throughout life to maintain physical and mental health and well-being. Tissue repair, healing, cell replacement, organ integrity, bone strength, brain function, enzyme production, integrity of hair, nails, skin and vital organs all require the ongoing availability of adequate growth hormone. After age 20, growth hormone production falls progressively and consistently at an average rate of about 14% per decade. By age 60, it is not uncommon to measure a growth hormone loss of 75% or more. Physical decline with age correlates directly with decreased secretion of growth hormone by the pituitary gland.



The Growing Impact of Growth Hormone...
Studies and real-life stories from everyday people show that growth hormone replacement therapy can have a dramatic effect on regaining youthful vitality, increasing muscle mass, improving immune function, bettering learning and memory, and lowering blood pressure.
On July 5, 1990, the New England Journal of Medicine published a clinical study on a drug that sent shock waves throughout the world. The drug-human growth hormone, HGH for short, or simply GH, a substance produced naturally by the pituitary gland-was hailed as a fountain of youth. Injections of synthetic human growth hormone had turned 12 men, ages 61 to 81, and with flabby, frail, fat-bulging bodies, into sleeker, stronger, younger selves.
After just six months of treatment, the men gained an average of 8.8 percent in lean body mass, and lost an average of 14.4 percent in fat mass. In addition, their skin thickened by 7.1 percent, the bone density of their lumbar spines increased by 1.6 percent, their livers grew by 19 percent, and their spleens by 17 percent. In language rarely used in conservative medical journals, Daniel Rudman, M.D., and his colleagues at the Medical College of Wisconsin, wrote, "The effects of six months of human growth hormone on lean body mass and adipose-tissue mass were equivalent in magnitude to the changes incurred during 10 to 20 years of aging."


If you would like to give either of these HRT's a try, here is a great quality source...
Go to MBI, Molecular Biologics, once there, to order DHEA, click on Lifestyle Management, then Glandular Support, and look for Bio-DHEA. To try GH, click MBI link, then Lifestyle Management, then Weight Management, look for Bio-GH.




Christopher Wiechert's Healthblogger is for educational or informational purposes only, and is not intended to diagnose or provide treatment for any condition. If you have any concerns about your own health, you should always consult with a health care professional. If you decide to use this information on your own, it's your constitutional right, but I assume no responsibility. The views expressed on this website are those of the health professionals & scientists I list or my own opinions and are not intended to replace any medical advice you may require. The contents have not been approved by the Pharmaceutical Association, the American Medical Association, or the Food and Drug Administration. This website may present views diametrically opposed to the views of such organizations. I also offer resources to products I formulate as well as those that I believe are of high value and quality. Profits from these recommendations are used to keep HealthBlogger free to those who read and appreciate the time and research that goes into these posts. It has been my experience over the last 35 years that if I offer reports and research without product recommendations, you will likely do 2 things. Pay more at the local health food store or worse yet, buy the product online or at the grocery or drug store, and end up not getting the right product or the quality you would expect. I only recommend companies I respect and order from myself. I consider this a value added service that I offer along with the research. If you find this a conflict of interest, please don't order from my links.

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